Rosuvastatin 5 mg 2-3 times weekly (n = 79) reduced TC 26%, TG 16% and LDL-C 32% (p < 0.001). The Alternate Day Versus Daily Dosing Data taken from [14,52]. J Postgrad Med. msorrent@medicine.bsd.uchicago.edu Financial & competing interests disclosure The author has no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. P et al. Ischemic Stroke May Hint at Underlying Cancer, Topol: US Betrays Healthcare Workers in Coronavirus Disaster, The 6 Dietary Tips Patients Need to Hear From Their Clinicians, 1 slice bread, 1 oz dry cereal, ½ cup cooked rice, pasta or cereal, 1 cup raw leafy vegetable, ½ cup cut-up raw or cooked vegetable, ½ cup vegetable juice, 1 medium fruit, ¼ cup dried fruit, ½ cup fresh, frozen or canned fruit, ½ cup fruit juice, Fat-free or low-fat milk and milk products, ⅓ cup (1½ oz), 2 tbsp peanut butter, 2 tbsp or ½ oz seeds, ½ cup dry beans or peas, 1 tsp soft margarine, 1 tbsp mayonnaise, 2 tbsp salad dressing, 1 tsp vegetable oil, 1 tbsp sugar, 1 tbsp jelly or jam, ½ cup sorbet and ices, 1 cup lemonade. FREE subscriptions for doctors and students... click here. Drug: Ezetimibe Ezetimibe 5 or 10 milligrams. please do not use GPnotebook. How many days in a row ibruprofen child? 4 Rosuvastatin is a long-acting statin with a mean terminal plasma elimination half-life of 19 hours. dosing in patients with prior statin intolerance. statin intolerance, checking effectiveness of non-daily statin dosing. Dietary therapy can be useful as adjunctive therapy to medication: Replacing animal protein with soy protein can reduce total cholesterol and LDL-C; 2 g/day of plant stanols and sterols in the diet reduces LDL-C by approximately 10%; Ingestion of 2–10 g/day of soluble fiber in the diet can reduce LDL-C by approximately 7%; The addition of fish oils to the diet for the prevention of cardiovascular events has been supported by a number of clinical trials; Individuals on a Mediterranean diet lose more weight compared with other dietary approaches and have lower total cholesterol and triglyceride levels, and higher HDL levels. 5 or 10 mg on alternate days, 80% of patients had no recurrence of myalgia, once weekly rosuvastatin, 5-20 mg, resulted in a mean LDL cholesterol Rosuvastatin, in conjunction with dietary measures, is used to treat high lipid levels in … If your doctor has prescribed the cholesterol-lowering medicine CRESTOR ® (rosuvastatin calcium) for you, it is important to take it exactly as prescribed by your doctor. If your doctor has prescribed the cholesterol-lowering medicine CRESTOR ® (rosuvastatin calcium) for you, it is important to take it exactly as prescribed by your doctor. Ann Pharmacother 2008;42:341-6. You will receive email when new content is published. All material on this website is protected by copyright, Copyright © 1994-2020 by WebMD LLC. Do not use more of it, do not use it more often, or do not use it for a longer time than your doctor ordered. Click the topic below to receive emails when new articles are available. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties. [7] A prospective trial of once-a-week rosuvastatin dosing in individuals with a history of myalgias on statin therapy achieved a >12% lowering of LDL-C and 80% of the patients were able to continue the medication without experiencing myalgias. To help keep this amount constant, do not miss any doses and take the medicine at the same time each day. Red yeast rice has been used as an alternative to statins in statin-intolerant patients. Please use this form to submit your questions or comments on how to make this article more useful to clinicians. Rosuvastatin is not recommended during pregnancy or breastfeeding, as there's no firm evidence it's safe. Also, this medicine works best if there is a constant amount in the blood.