Sun Pharmaceutical Industries, Inc. Lithium is not metabolized. Each 300 mg tablet for oral administration contains: lithium carbonate 300 mg and is white to off-white, circular, biconvex, uncoated tablet debossed with “430” on one side and break line on other side. Titrate to serum lithium concentrations between 0.8 and 1.2 mEq/L, which may be achieved in adults with: Obtain serum lithium concentrations regularly until the serum concentration and clinical condition of the patient has stabilized [see Dosage and Administration (2.6)]. If you faint or feel abnormal heartbeats, talk to your healthcare provider right away. Dosage recommendations for lithium in patients 12 years and older are similar to that of adults [see Dosage and Administration (2.5)]. Sun Pharmaceutical Industries Ltd. For more information about Lithium Carbonate Tablets, call 1-800-818-4555. For more severe hyponatremia (serum Na < 115 mEq/L), stupor, neuromuscular hyperexcitability, hyperreflexia, seizures, coma, and death can result. de los trastornos bipolares. What should I tell my healthcare provider before taking Lithium Carbonate Tablets? Lithium is an element of the alkali-metal group with atomic number 3, atomic weight 6.94 and an emission line at 671 nm on the flame photometer. You can ask your pharmacist or healthcare provider for information about Lithium Carbonate Tablets that is written for healthcare professionals. Available for Android and iOS devices. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other treatment. low levels of sodium (salt) in your blood (hyponatremia). Protect from moisture. The toxic concentrations for lithium (≥ 1.5 mEq/L) are close to the therapeutic concentrations [see Warnings and Precautions (5.1)]. Acute mania: Adults: Treatment should be initiated in hospital where regular monitoring of plasma lithium levels can be conducted. Symptoms include hypotonia, respiratory distress syndrome, cyanosis, lethargy, feeding difficulties, depressed neonatal reflexes, neonatal depression, apnea, and bradycardia. Manufactured by: Talk to your healthcare provider about these activities. Your healthcare provider will do certain blood tests before and while you take Lithium Carbonate Tablets. Lithium Carbonate Tablets USP Neurological signs of lithium toxicity range from mild neurological adverse reactions such as fine tremor, lightheadedness, and weakness; to moderate manifestations like apathy, drowsiness, hyperreflexia, muscle twitching, and slurred speech; and severe manifestations such as clonus, confusion, seizure, coma and death. [see Dosage and Administration (2.6), Warning and Precautions (5.3)]. More frequent serum lithium concentration monitoring. Enf. Lithium Toxicity, Inform patients on adverse reactions related to lithium toxicity that require medical attention. Ask if you are not sure about the medicines you take. Amiloride may be considered as a therapeutic agent for lithium-induced nephrogenic diabetes insipidus. Lithium toxicity is closely related to serum lithium concentrations, and can occur at doses close to therapeutic concentrations. Lithium can also cause renal tubular acidosis, resulting in hyperchloremic metabolic acidosis. Monitor patients closely for symptoms of toxicity of methyldopa, phenytoin, and carbamazepine. Routine urinalysis and other tests may be used to evaluate tubular function (e.g., urine specific gravity or osmolality following a period of water deprivation, or 24-hour urine volume) and glomerular function (e.g., serum creatinine, creatinine clearance, or proteinuria). Gastrointestinal: anorexia, nausea, vomiting, diarrhea, gastritis, salivary gland swelling, abdominal pain, excessive salivation, flatulence, indigestion. Do not give Lithium Carbonate Tablet to other people, even if they have the same symptoms you have. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2-4% and 15-20%, respectively. Advise patients and caregivers to watch for signs of early toxicity and to discontinue lithium and immediately inform their health care provider if they occur. m Carbonate Tablets can cause serious side effects, including too much lithium in your blood (lithium toxicity). Early voluntary reports to international birth registries suggested an increase in cardiovascular malformations, especially for Ebstein’s anomaly, with first trimester use of lithium. NSAID decrease renal blood flow, resulting in decreased renal clearance and increased serum lithium concentrations. These are not all the possible side effects of Lithium Carbonate Tablets. The risk of acute toxicity is increased with a recent onset of concurrent illness or with the concomitant administration of drugs which increase lithium serum concentrations by pharmacokinetic interactions [see Drug Interactions (7)]. Early symptoms of lithium toxicity can usually be treated by reduction or cessation of lithium, before restarting treatment at a lower dose 24 to 48 hours later [see Overdosage (10)]. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. Postmarketing cases consistent with nephrotic syndrome in patients with or without CTIN have also been reported. It is not known if Lithium Carbonate Tablet is safe and effective in children. Do not use desvenlafaxine within 14 days of quiting an MAOI meant to treat psychological conditions. w should I take Lithium Carbonate Tablets? increased pressure in the brain and swelling in the eye (pseudotumor cerebri) that can cause vision problems or blindness.