If you subscribe to any of our print newsletters and have never activated your online account, please activate your account below for online access. It's a measure of weight that includes height. Please note: If you have a promotional code you'll be prompted to enter it prior to confirming your order. All drugs have side effects. What can we help you find? Patients tolerating the once-a-week regimen experienced a 17% reduction in total cholesterol, 23% reduction in low-density lipoprotein cholesterol, 12% reduction in triglycerides, and a 5% increase in high-density lipoprotein cholesterol (all p <0.001), during a mean follow-up of 4 months +/- 2. once weekly rosuvastatin, 5-20 mg, resulted in a mean LDL cholesterol reduction of 29% among 8 intolerant patients without any incidence of myopathy non-daily rosuvastatin and atorvastatin seem tolerable - the use of non daily statin dosing may help lower LDL cholesterol levels in patients with statin intolerance Effects of once weekly rosuvastatin among patients with a prior statin intolerance. The aim of this study was to evaluate the efficacy of rosuvastatin twice weekly in 40 patients intolerant to daily statins. Figuring out if these are due to a statin can be tricky. The balance sheet for Crestor and other statins looks like this: These drugs cut the risk of heart attack, angina (chest pain), stroke, and death from cardiovascular disease by 30%. Rosuvastatin twice weekly alone or added to other lipid-lowering medications decreased total cholesterol by 19%, low-density lipoprotein cholesterol by 26%, and triglycerides by 14% (p <0.01 for all). Muscle pains and aches are part of everyday life for some. Clipboard, Search History, and several other advanced features are temporarily unavailable. If any of these apply to you, it's prudent to start with a low-dose statin and slowly work your way up to what's needed to get your cholesterol to a safe level while having your doctor closely monitor you for problems. Sometimes just taking a break, then restarting the same statin at the same dose is enough to make the problem disappear. Can acupuncture help my menopause symptoms? In addition to Crestor, the other statins are Lescol (fluvastatin), Lipitor (atorvastatin), Mevacor (lovastatin), Livalo (pitavastatin), Pravachol (pravastatin), and Zocor (simvastatin). Get the latest research from NIH: https://www.nih.gov/coronavirus. Get health information and advice from the experts at Harvard Medical School. Patients tolerating the once-a-week regimen experienced a 17% reduction in total cholesterol, 23% reduction in low-density lipoprotein cholesterol, 12% reduction in triglycerides, and a 5% increase in high-density lipoprotein cholesterol (all p <0.001), during a mean follow-up of 4 months ± 2. They cause muscle pain in under 5% of the people who take them, and these pains often stop by themselves even with continued statin use. Androgens, the family of male sex hormones that includes testosterone, function as a fuel for growth in normal development. Can adopting a healthier diet help fight prostate cancer? J Clin Lipidol. NIH Curr Cardiol Rep. 2015 May;17(5):27. doi: 10.1007/s11886-015-0582-z. The primary efficacy outcome was the difference in the mean percentage change in LDL from baseline between rosuvastatin and placebo. Be aware of muscle pain, cramps, stiffness, spasms, and weakness that can't be explained by arthritis, recent strenuous exercise, a fever, a fall, or other common causes. Upsides. BMI stands for "body mass index." Epub 2008 Feb 19. Kennedy SP, Barnas GP, Schmidt MJ, Glisczinski MS, Paniagua AC. According to Consumer Reports Health Best Buy Drugs, 40 mg of lovastatin (Mevacor) is likely to reduce LDL cholesterol on average about 31% whereas 5 mg of Crestor would lower LDL cholesterol between 39% and 46%.